In some mitochondrial genetic codes, which codon is reinterpreted to code for methionine instead of isoleucine?

Study for the DNA Structure, Replication, Transcription and Translation Test with flashcards and multiple choice questions. Each question offers hints and explanations. Prepare thoroughly and excel in your exam!

Multiple Choice

In some mitochondrial genetic codes, which codon is reinterpreted to code for methionine instead of isoleucine?

Explanation:
Mitochondria use a genetic code that differs from the universal code, so some codons are read differently because the tRNA set and translation machinery have evolved. In many mitochondrial codes, the codon AUA, which normally stands for isoleucine in the standard code, is reassigned to encode methionine. AUG still codes for methionine and is often used as the start signal, while AUU and AUC continue to code for isoleucine in these mitochondria. This shift reflects how mitochondrial translation adapts to its limited tRNA repertoire. So AUA is read as methionine in these mitochondrial contexts.

Mitochondria use a genetic code that differs from the universal code, so some codons are read differently because the tRNA set and translation machinery have evolved. In many mitochondrial codes, the codon AUA, which normally stands for isoleucine in the standard code, is reassigned to encode methionine. AUG still codes for methionine and is often used as the start signal, while AUU and AUC continue to code for isoleucine in these mitochondria. This shift reflects how mitochondrial translation adapts to its limited tRNA repertoire. So AUA is read as methionine in these mitochondrial contexts.

Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy